Cardiac ketone body metabolism

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منابع مشابه

Ketone-body metabolism during the neonatal period.

Garber, A. J., Menzel, P. H., Boden, G. & Owen, 0. E. (1974) J. Clin. Invest. 54,981-989 Long, C . L., Spencer, J. L., Kinney, J. M. & Geiger, J. W. (1971) J. Awl. Physiol. 31.102-109 Owen, 0. E., Reichard, G. A., Jr., Boden, G., Patel, M. S. & Trapp, V. E. (1978) in Advances in Modern Nutrition: Diabetes, Obesity and Vascular Disease (Katzen, H. M . & Mahler, R. J., eds.), vol. 2, pp. 517-550,...

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Recent developments in ketone-body metabolism.

There is now no doubt that ketone bodies (acetoacetate and D-3-hydroxybutyrate) are important oxidizable substrates for peripheral tissues, especially the brain. Although oxidation is the major fate of ketone bodies, more recent evidence suggests that ketone bodies can act as lipogenic substrates in certain tissues, notably the developing brain and the lactating mammary gland. Apart from their ...

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Ketone-body metabolism in tumour-bearing rats.

During starvation for 72 h, tumour-bearing rats showed accelerated ketonaemia and marked ketonuria. Total blood [ketone bodies] were 8.53 mM and 3.34 mM in tumour-bearing and control (non-tumour-bearing) rats respectively (P less than 0.001). The [3-hydroxybutyrate]/[acetoacetate] ratio was 1.3 in the tumour-bearing rats, compared with 3.2 in the controls at 72 h (P less than 0.001). Blood [glu...

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Ketone body metabolism and cardiovascular disease.

Ketone bodies are metabolized through evolutionarily conserved pathways that support bioenergetic homeostasis, particularly in brain, heart, and skeletal muscle when carbohydrates are in short supply. The metabolism of ketone bodies interfaces with the tricarboxylic acid cycle, β-oxidation of fatty acids, de novo lipogenesis, sterol biosynthesis, glucose metabolism, the mitochondrial electron t...

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Ketone-body metabolism after partial hepatectomy in the rat.

Fed or 24 h-starved rats were subjected to two-thirds partial hepatectomy or sham-operation and subsequently starved for 4, 14 or 24 h. Despite high plasma fatty acid concentrations, the partially hepatectomized rats failed to respond to post-operative starvation with increased blood and liver ketone-body concentrations or to maintain the high ketone-body concentrations associated with pre-oper...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

سال: 2020

ISSN: 0925-4439

DOI: 10.1016/j.bbadis.2020.165739